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ZEN Nasal Spray is MitoZen’s strongest formula made from different medicinal plants from the Amazon to calm and quiet the mind, as well as to reduce anxiety and stress. ZEN EO is made with Ultra Nano Liposomal terpenes & essential oils. ZEN CBD Nasal Spray contains essential oils, terpenes and full spectrum NeuroHemp. The Zen formulas are powerful in the ability to calm the mind and allow for maximum vagal activation (stimulation of the vagal nerve). You will experience a powerful afterglow effect, following the initial temporary burning feeling after administration. After the slight burn goes away, the effect mimics meditation, breath work and sauna/cold exposure. Improved vagus function increases the brain blood flow, and affects the release of several stimulatory neurotransmitter, leading to positive effects. (Note: contains very small amounts of nicotine as part of the delivery system to the brain)